Market Scenario 

Japan Epigenetics Market is estimated to witness a rise in revenue from US$ 23.6 Mn in 2021 to US$ 48.6 Mn by 2027. The market is registering at a CAGR of 12.8% during the forecast period 2022-2027. 

Epigenetics is a branch of genetics concerned with the study of cellular and physiological trait variations caused by behaviors and environmental factors that impact the way the persons genes work. Moreover, epigenetics market growth is primarily attributed to the increasing number of chronic diseases that requires a high amount of medical examination, coupled with the technological enhancements in treatment. Also, the growing geriatric population, increasing demand for R&D activities and favorable government supports for epigenetics procedures is creating a huge demand for the market of epigenetics. Furthermore, the growing technological advancements such as AI and adoption of machine learning in epigenetics has shown a tremendous growth opportunity for the market.

The major factor responsible for the growth of the Japan epigenetics market includes growing of R&D expenditure in the pharmaceutical & biopharmaceutical industry and growing adoption of epigenetics for cancer treatment. The pharmaceutical industry’s activities have significant socio-economic impacts on society in the form of investments in R&D and manufacturing which results in driving the growth of drug discovery services, thereby augmenting the epigenetics market. Moreover, epigenetics is a way to diagnose and treat cancer and other conditions, as it to work well with radiation and chemotherapy as these drugs may make cancer cells more sensitive to these therapies. Furthermore, the rising number of initiatives taken by government bodies, universities and pharmaceutical and biotechnology companies in order to encourage researches related to epigenetics is one of the major factors which positively impact market growth in the Japan. However, high costs of epigenetics instruments and dearth of skilled workforce hinder their wide adoption, which is expected to restrict market growth during the forecast period.4

Report Summary

The study of the Japan Epigenetics Market considers various market determinants, industry value chain analysis and competitor analysis of the market. The report discusses the analysis of the epigenetics industry for the period 2017-2027, where the base year is 2021 and the forecast period is 2022-2027. The report provides a detailed analysis of the Japan Epigenetics Market across 9 Chapters and 82 pages. The report includes data presentation across 8 tables and 23 statistical figures. 

The report provides PESTLE analysis, which is a tool to examine the external market environment factors that have an impact on the industry. The PESTLE analysis examines the Political, Economic, Social, Technological, Environmental and Legal factors in the external environment. Thus, sufficiently examining the threats and weaknesses of the industry. The research report also provides Porter’s five forces analysis wherein bargaining power of buyers and competitive rivalry is high. 

The subsequent section provides details of the market analysis based on different segments such as product type, technology, application, end-users. The report includes detailed study of value chain of the industry. It includes raw material providers, manufacturing, distributors and end users. The report also covers extensively about the key competitors in the market for epigenetics.

Impact of COVID-19 on Japan Epigenetics Market 

Japan Epigenetics market is expected to witness a slight decline of approx. 3.2% in 2020, in the recent outbreak of the COVID-19 pandemic. The novel COVID-19 has seen a significant impact on the epigenetics market. Every element has been affected, from raw material supplier to manufacturer and other end users. Factories and production facility have been forced to remain closed due to lockdown and social distancing measures, resulting in a sharp drop in the sales of epigenetic services, instrument and others. Moreover, epigenetics devices and instrument manufacturers rely on supply chain, over-rely on suppliers of key components and their weak negotiation power will lead to high precision components and others. Furthermore, the significant decline in skilled professionals and a decrease in research activity due to laboratory closures and reduced clinical testing have all affected the epigenetics products market.

However, the market will gain its traction with the investments in new technologies like adoption of automated devices with the implementation of AI and machine learning, which will foster the epigenetics market growth. Nevertheless, post-COVID-19, the demand for epigenetics will further grow at an unprecedented rate, with gradual expansion in the market value during the forecast period.

Key Takeaways from the Japan Epigenetics Market Report

• In terms of product type, the kits segment holds the largest share in the Japan epigenetics market in 2021 and is also anticipated to hold the highest CAGR over the forecast period owing to the high usage of kits in epigenetics mechanisms.
• Based on technology, the DNA methylation segment is anticipated to hold the largest market share over the forecast period owing to the high usage of this technique in the research and academic institutes. Moreover, bromodomains segment is projected to hold the highest CAGR over the forecast period.
• On the basis of application, the oncology segment dominated the Japan epigenetics market in 2021 and is also anticipated to grow at the highest CAGR over the forecast period owing to the rising applications of epigenetic in cancer treatment. The continuous research in the oncology field to spur the treatment process is further expected to drive the segmental growth in the near future.
• By end-users, the pharmaceutical & biotechnology companies held the highest share in the Japan epigenetics market in 2021 due to R&D for drug resistance developed by microorganisms, oncology, molecular aspects of cancer and drug discovery for non-oncology applications. Moreover, the academic and research institutes segment is expected to project the highest CAGR during the forecast period.

Company Profile 

• Epigeneron, Inc. was established in 2015. They develop drugs which target intractable diseases caused by abnormal regulation of genome functions such as transcription and epigenetic regulation. In addition, epigeneron is also active in the development of novel biotechnologies based on molecular biology. The company’s core technologies include locus-specific ChIP and ORNi-PCR, enabling patients to get treatment against diseases including cancer, fibrosis, disorders of the central nervous system and infectious diseases.
• Illumina, Inc. provides sequencing and array-based solutions for genetic and genomic analysis. The company provides instruments and consumables used in genetic analysis, and genotyping and sequencing services, instrument service contracts and development and licensing agreements. Moreover, in terms of business revenue segmentation, products segment holds the largest market share.
• Daiichi Sankyo Co. Ltd. is mainly engaged in the manufacturing and sale of pharmaceuticals. The Company is involved in the research, development, manufacturing and sale of pharmaceuticals, as well as the provision of intermediates and basic materials for pharmaceutical. Also, Daiichi Sankyo is primarily focused on developing novel therapies for people with cancer as well as other diseases with high unmet medical needs. Furthermore, Japan holds the largest share in the market in terms of geographical revenue segmentation.

Competitive Landscape

The key players in the Japan Epigenetics Market are Epigenereon, National Institute of Genetics, Rhelixa Inc., RIKEN, Illumina, Inc., Daiichi Sankyo Company Limited, Takeda Pharmaceutical Company Limited and Abcam PLC among others. Through extensive research, it is found that big players have adopted various competitive strategies such as mergers & acquisitions in order to have a grip of emerging market. Furthermore, leading companies are expanding their geographical boundaries by acquiring small brands and domestic companies.

Segmentation Overview 

Japan Epigenetics Market is segmented based on product type, technology, application, end-users and country. The industry trends in the epigenetics market are sub-divided into different categories in order to get a holistic view of the Japan marketplace. 

Following are the different segments of the Japan Epigenetics Market:

By Product Type segment of the Japan Epigenetics Market is sub-segmented into:

• Reagents
• Kits
  • Bisulfite Conversion Kits
  • ChIP Kits
  • RNA Kit
  • Others
• Instruments
• Software Tools
  • EpiGRAPH
  • BiQ Analyzer
  • RnBeads
  • Others
• Enzymes
• Proteins & Peptides
• Antibodies
• Services

By Technology segment of the Japan Epigenetics Market is sub-segmented into:

• DNA Methylation
• Histone Methylation
• Histone Acetylation
• Bromodomains
• Non-coding RNA
• Other

By Application segment of the Japan Epigenetics Market is sub-segmented into:

• Oncology
• Non-oncology
  • Cardiovascular diseases
  • Neurodegenerative
  • Autoimmune

By End-Users segment of the Japan Epigenetics Market is sub-segmented into:

• Academic and Research Institutes
• Pharmaceutical & Biotechnology Companies
• Contract Research Organizations (CROs)
• Research and consulting firms